Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.82 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.82 |
| ▸ | GABRP | O00591 | 9/20 | 0.82 |
| ▸ | GABRD | O14764 | 9/20 | 0.82 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.82 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.82 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.82 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.82 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.82 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.82 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.82 |
| ▸ | GABRE | P78334 | 9/20 | 0.82 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.82 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.82 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.82 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | G6PD | P11413 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904078 | 1.00 | GABRA1 (0.82) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL22834378 | 0.92 | GABRA1 (0.70) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL22834399 | 0.92 | GABRA1 (0.70) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL3124023 | 0.90 | GABRP (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL23346583 | 0.90 | GABRP (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL23468933 | 0.90 | GABRP (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL21091386 | 0.90 | GABRP (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL14871130 | 0.90 | GABRP (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL23344276 | 0.90 | GABRP (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL19650972 | 0.90 | GABRP (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728285-B1 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | SAGE THERAPEUTICS LLC (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20250171492-A1 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | SAGE THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| US-20220315621-A1 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | SAGE THERAPEUTICS, INC. | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171492-A1 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | ATP6V1B2, RAB9A, GRIN2B | GABRA1 960/4885GABRB2 703/4885GABRP 1101/4885 |
| US-20220315621-A1 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | ATP6V1B2, RAB9A, GRIN2B | GABRA1 960/4885GABRB2 703/4885GABRP 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.