Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.71 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 4/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | XDH | P47989 | 4/20 | 0.71 |
| ▸ | IPMK | Q8NFU5 | 4/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942485 | 0.89 | KMT2A (0.68) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL20426 | 0.83 | POLH (1.00) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL28256564 | 0.83 | POLH (1.00) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL29376494 | 0.83 | POLH (1.00) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL30045580 | 0.83 | POLH (1.00) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL29352380 | 0.83 | POLH (1.00) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL1659262 | 0.82 | POLH (0.97) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL31539190 | 0.82 | POLH (0.97) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL31258014 | 0.82 | POLH (0.97) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| Luteolin SCHEMBL31168048 | 0.82 | POLH (0.97) | POLHMEN1KMT2ACYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115261422-A | Preparation method and application of new species thiolutin | 塔里木大学 | 2022-11-01 | — | — | CN | disclosed |