Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 5/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.44 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.44 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GSTA1 | P08263 | 5/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.38 |
| ▸ | PTPRC | P08575 | 4/20 | 0.38 |
| ▸ | HMGCR | P04035 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.36 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.34 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986985 | 1.00 | PTPRB (0.44) | PTPRBPTPN2PTPN1PTPN11PTPN4 | |
| SCHEMBL2992702 | 0.79 | POLB (0.34) | MEN1KMT2APOLBACHECD69 | |
| SCHEMBL2990792 | 0.79 | POLB (0.34) | MEN1KMT2APOLBACHECD69 | |
| SCHEMBL6067643 | 0.76 | GSTA1 (0.44) | PTPRBPTPN2PTPN1PTPN11GSTA1 | |
| SCHEMBL2455787 | 0.74 | HMGCR (0.57) | MEN1KMT2APOLBHMGCRNR1I2 | |
| SCHEMBL12012729 | 0.72 | POLB (0.43) | MEN1KMT2APOLBHMGCRNR1I2 | |
| SCHEMBL2534198 | 0.71 | TSHR (0.40) | MEN1KMT2APOLBACHE | |
| SCHEMBL2990273 | 0.70 | PTPRB (0.55) | PTPRBPTPN2PTPN1PTPN11PTPN4 | |
| SCHEMBL2984001 | 0.70 | PTPRB (0.55) | PTPRBPTPN2PTPN1PTPN11PTPN4 | |
| SCHEMBL12229694 | 0.69 | TDP1 (0.39) | MEN1KMT2APOLBNR1I2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252954-B2 | Processes for the preparation of calixarene derivatives | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2012-08-28 | — | — | US | disclosed |
| US-20100185022-A1 | PROCESSES FOR THE PREPARATION OF CALIXARENE DERIVATIVES | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100185022-A1 | PROCESSES FOR THE PREPARATION OF CALIXARENE DERIVATIVES | CALD1, CANX, CALU | PTPRB 250/4885PTPN2 930/4885PTPN1 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.