Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTA1 | P08263 | 5/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 2/20 | 0.38 |
| ▸ | CD14 | P08571 | 2/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 4/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | PTPRB | P23467 | 4/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990792 | 0.76 | POLB (0.34) | — | |
| SCHEMBL2992702 | 0.76 | POLB (0.34) | — | |
| SCHEMBL2990563 | 0.76 | PTPRB (0.44) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL2986985 | 0.76 | PTPRB (0.44) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL14353074 | 0.72 | TLR4 (0.43) | GSTA1GSTP1CYP3A4TLR4CD14 | |
| SCHEMBL6067644 | 0.72 | TLR4 (0.43) | GSTA1GSTP1CYP3A4TLR4CD14 | |
| SCHEMBL6067581 | 0.72 | GSTA1 (0.43) | GSTA1GSTP1CYP3A4TLR4CD14 | |
| SCHEMBL18334409 | 0.71 | MEN1 (0.51) | CYP3A4 | |
| SCHEMBL6067586 | 0.69 | TLR4 (0.42) | GSTA1GSTP1TLR4CD14LY96 | |
| SCHEMBL30702676 | 0.68 | GSTA1 (0.57) | GSTA1GSTP1CYP3A4TLR4CD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006056182-A1 | NOVEL ACTIVE SUBSTANCES FOR TREATING, DIAGNOSING AND PREVENTING MACULAR DEGENERATION | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2006-06-01 | — | — | WO | disclosed |