Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1184986 | 1.00 | SYK (0.43) | SYKADRB1KDM4ELMNAALDH1A1 | |
| SCHEMBL18581 | 0.85 | LMNA (0.38) | SYKKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL13019476 | 0.82 | LMNA (0.39) | SYKKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6250182 | 0.80 | ADRB1 (0.40) | SYKADRB1LRRK2HDAC3NCOR1 | |
| SCHEMBL8345900 | 0.79 | HDAC3 (0.42) | SYKADRB1KDM4EALDH1A1LRRK2 | |
| SCHEMBL23121276 | 0.79 | ALOX15 (0.40) | LMNAALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL750287 | 0.77 | CCNT1 (0.38) | KDM4ELMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL12933370 | 0.77 | HDAC3 (0.40) | SYKADRB1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL12963514 | 0.77 | HDAC3 (0.40) | SYKADRB1KDM4ELMNAALDH1A1 | |
| SCHEMBL16538500 | 0.76 | KCNH2 (0.42) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022211595-A1 | OXADIAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2022-10-06 | — | — | WO | disclosed |