Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 7/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29906009 | 0.80 | SYK (0.43) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL1184986 | 0.80 | SYK (0.43) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL8345900 | 0.76 | HDAC3 (0.42) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL12933370 | 0.73 | HDAC3 (0.40) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL12963514 | 0.73 | HDAC3 (0.40) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL17049228 | 0.72 | ADRB1 (0.43) | ADRB1PKMSYKLOXL2TAS2R14 | |
| SCHEMBL29390964 | 0.72 | HDAC3 (0.42) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL29712950 | 0.72 | ALDH1A1 (0.47) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL28040342 | 0.72 | SYK (0.42) | ADRB1LRRK2HDAC3NCOR1HDAC4 | |
| SCHEMBL4720895 | 0.71 | HDAC3 (0.41) | ADRB1HDAC3NCOR1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |