Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.79 |
| ▸ | MAOA | P21397 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.56 |
| ▸ | F12 | P00748 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581074 | 1.00 | MAOB (0.79) | MAOBMAOAMEN1KMT2ACTDSP1 | |
| SCHEMBL5717527 | 0.88 | MAOB (1.00) | MAOBMAOAMEN1KMT2ACA12 | |
| SCHEMBL31672154 | 0.87 | POLB (0.80) | MAOBMAOAMEN1KMT2ACTDSP1 | |
| SCHEMBL26987736 | 0.87 | CA12 (0.80) | MAOBMAOAMEN1KMT2ACTDSP1 | |
| SCHEMBL2983118 | 0.83 | KDM4E (0.60) | MAOBMAOAMEN1KMT2ACTDSP1 | |
| SCHEMBL6578674 | 0.81 | CYP2C19 (0.62) | MAOBMAOAMEN1KMT2ACTDSP1 | |
| Propene SCHEMBL27951962 | 0.81 | MAOB (0.85) | MAOBMAOAMEN1KMT2ACA12 | |
| SCHEMBL7163440 | 0.80 | MIF (0.67) | MAOBMAOAKMT2ACA12CA9 | |
| SCHEMBL1091343 | 0.80 | MAOA (0.51) | MAOBMAOAMEN1KMT2ACTDSP1 | |
| SCHEMBL27085612 | 0.79 | MIF (0.65) | MAOBMAOAMEN1KMT2ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124986-B1 | NITROCOUMARINS FOR DETECTING ALL MICRO-ORGANISMS | BIOMERIEUX SA (FR) | 2004-05-06 | — | — | EP | claimed |
| US-6555332-B2 | Calibration using fluorescence signals | BIOMERIEUX S.A. (FR) | 2003-04-29 | — | — | US | claimed |
| US-20020031795-A1 | Nitrocoumarins for detecting all micro-organisms | BIOMERIEUX S.A. (FR) | 2002-03-14 | — | — | US | claimed |
| EP-4204398-A2 | CONJUGATES INCLUDING A DETECTABLE MOIETY | Ventana Medical Systems, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| US-20230192658-A1 | CONJUGATES INCLUDING A DETECTABLE MOIETY | VENTANA MEDICAL SYSTEMS, INC. | 2023-06-22 | — | — | US | disclosed |
| CN-115989221-A | Conjugates comprising a detectable moiety | 文塔纳医疗系统公司 | 2023-04-18 | — | — | CN | disclosed |
| WO-2022043491-A2 | CONJUGATES INCLUDING A DETECTABLE MOIETY | VENTANA MEDICAL SYSTEMS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |
| CN-104651476-B | Novel nitroreductase substrates | 生物梅里埃公司 | 2020-02-18 | — | — | CN | disclosed |
| US-20150211044-A1 | QUICK METHOD FOR DETECTING ENYZMES AND MICROORGANISMS | BIO-RAD EUROPE GMBH (CH) | 2015-07-30 | — | — | US | disclosed |
| US-9012167-B2 | Quick method for detecting enzymes and microorganisms | BIO-RAD INNOVATIONS (FR) | 2015-04-21 | — | — | US | disclosed |
| US-20130089883-A1 | QUICK METHOD FOR DETECTING ENYZMES AND MICROORANISMS | BIO-RAD INNOVATIONS (FR) | 2013-04-11 | — | — | US | disclosed |
| US-8211662-B2 | Nitroreductase enzymatic substrates | BIOMERIEUX (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20100221764-A1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | BIOMERIEUX (FR) | 2010-09-02 | — | — | US | disclosed |
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | AUCKLAND UNISERVICES LIMITED | 2010-07-08 | — | — | US | disclosed |
| WO-2008030120-A1 | A METHOD FOR THE FLUORESCENT DETECTION OF NITROREDUCTASE ACTIVITY USING NITRO-SUBSTITUTED AROMATIC COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |
| EP-1124986-B1 | NITROCOUMARINS FOR DETECTING ALL MICRO-ORGANISMS | BIOMERIEUX SA (FR) | 2004-05-06 | — | — | EP | disclosed |
| US-6555332-B2 | Calibration using fluorescence signals | BIOMERIEUX S.A. (FR) | 2003-04-29 | — | — | US | disclosed |
| US-20020031795-A1 | Nitrocoumarins for detecting all micro-organisms | BIOMERIEUX S.A. (FR) | 2002-03-14 | — | — | US | disclosed |
| EP-1124986-A1 | NITROCOUMARINS FOR DETECTING ALL MICRO-ORGANISMS | Biomerieux S.A. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000028073-A1 | NITROCOUMARINS FOR DETECTING ALL MICRO-ORGANISMS | BIOMERIEUX S.A. (FR) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192658-A1 | CONJUGATES INCLUDING A DETECTABLE MOIETY | CD2BP2, CD47, CD44 | MAOB 1617/4885MAOA 1678/4885MEN1 647/4885 |
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | BLVRB, POR, CBR3 | MAOB 26/4885MAOA 22/4885MEN1 4838/4885 |
| US-20020031795-A1 | Nitrocoumarins for detecting all micro-organisms | CBR3, CYB5R3, CBR1 | MAOB 130/4885MAOA 149/4885MEN1 1923/4885 |
| US-20100221764-A1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | CBR1, CBR3, XDH | MAOB 300/4885MAOA 328/4885MEN1 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.