Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434908 | 1.00 | TLR2 (0.57) | TLR2KMT2APTPN1TNFCASP3 | |
| SCHEMBL27093960 | 0.96 | TLR2 (0.62) | TLR2KMT2APTPN1TNFCASP3 | |
| SCHEMBL27093964 | 0.96 | TLR2 (0.62) | TLR2KMT2APTPN1TNFCASP3 | |
| SCHEMBL38664780 | 0.94 | TLR2 (0.54) | TLR2KMT2APTPN1TNFCASP3 | |
| SCHEMBL7208037 | 0.92 | TLR2 (0.54) | TLR2KMT2APTPN1TNFCASP3 | |
| SCHEMBL16327986 | 0.90 | TLR2 (0.59) | TLR2TNFMDM2 | |
| SCHEMBL29907904 | 0.89 | CASP3 (0.55) | TLR2KMT2ATNFCASP3MDM2 | |
| SCHEMBL30919288 | 0.89 | KMT2A (0.54) | TLR2KMT2APTPN1CASP3MDM2 | |
| SCHEMBL4300738 | 0.89 | KMT2A (0.58) | TLR2KMT2APTPN1CASP3MDM4 | |
| SCHEMBL20504185 | 0.89 | KMT2A (0.58) | TLR2KMT2APTPN1CASP3MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214297-A1 | COMPOUNDS FOR DELIVERING GLUTATHIONE TO A TARGET AND METHODS OF MAKING AND USING THE SAME | OREGON STATE UNIVERSITY (US) | 2017-12-14 | — | — | WO | disclosed |
| WO-2015073678-A1 | COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | ENDOCYTE, INC. (US) | 2015-05-21 | — | — | WO | disclosed |
| US-6372883-B1 | FOR THERAPY AND PROPHYLAXIS OF INFECTIONS CAUSED BY HEPATITIS C, HEPATITIS G AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2002-04-16 | — | — | US | disclosed |