Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907904 | 0.88 | CASP3 (0.55) | CASP3KMT2ATLR2MDM2 | |
| SCHEMBL765306 | 0.84 | TLR2 (0.55) | CASP3KMT2ATLR2MDM2 | |
| SCHEMBL4598995 | 0.83 | CASP3 (0.57) | CASP3KMT2AMDM2 | |
| SCHEMBL30954537 | 0.83 | TLR2 (0.49) | CASP3KMT2ATLR2 | |
| SCHEMBL30824463 | 0.83 | TLR2 (0.56) | CASP3TLR2MDM2 | |
| SCHEMBL10081723 | 0.83 | TLR2 (0.56) | CASP3TLR2MDM2 | |
| SCHEMBL8223034 | 0.83 | TLR2 (0.56) | CASP3TLR2MDM2 | |
| SCHEMBL7713440 | 0.82 | TLR2 (0.57) | CASP3KMT2ATLR2MDM2 | |
| SCHEMBL5202723 | 0.82 | TLR2 (0.59) | CASP3KMT2ATLR2MDM2 | |
| SCHEMBL30434908 | 0.82 | TLR2 (0.57) | CASP3KMT2ATLR2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | HAVCR2, ADAR, NSUN2 | CASP3 760/4885KMT2A 3406/4885TLR2 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.