Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.62 |
| ▸ | PPARG | P37231 | 9/20 | 0.62 |
| ▸ | PPARD | Q03181 | 2/20 | 0.60 |
| ▸ | CTSS | P25774 | 9/20 | 0.53 |
| ▸ | CTSK | P43235 | 7/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463195 | 1.00 | PPARA (0.62) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL29907919 | 0.86 | CTSS (0.60) | PPARAPPARGCTSSCTSKPTPN1 | |
| SCHEMBL29842925 | 0.86 | CTSS (0.60) | PPARAPPARGCTSSCTSKPTPN1 | |
| SCHEMBL3812341 | 0.86 | CTSS (0.60) | PPARAPPARGCTSSCTSKPTPN1 | |
| SCHEMBL17912348 | 0.86 | CTSS (0.60) | PPARAPPARGCTSSCTSKPTPN1 | |
| SCHEMBL3812344 | 0.86 | CTSS (0.60) | PPARAPPARGCTSSCTSKPTPN1 | |
| SCHEMBL9161711 | 0.84 | PPARA (0.67) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL5001306 | 0.82 | PPARA (0.62) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL5001310 | 0.82 | PPARA (0.62) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL11327876 | 0.82 | PPARA (0.65) | PPARAPPARGPPARDCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | PPARA 3971/4885PPARG 4143/4885PPARD 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.