Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826584 | 1.00 | GAA (0.64) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8314477 | 0.84 | MEN1 (0.63) | GAAMAPTMEN1KMT2ATSHR | |
| SCHEMBL18294029 | 0.83 | TSHR (0.59) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL26333757 | 0.83 | ATM (0.62) | GAAMAPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6207654 | 0.83 | MEN1 (0.61) | GAAMAPTMEN1KMT2ATSHR | |
| SCHEMBL19751948 | 0.81 | ATM (0.65) | GAAMAPTMEN1KMT2ATSHR | |
| SCHEMBL27766295 | 0.81 | ATM (0.60) | GAAMAPTMEN1KMT2ATSHR | |
| SCHEMBL9524205 | 0.81 | CTSD (0.54) | GAAMAPTALDH1A1CTSD | |
| SCHEMBL1010680 | 0.80 | LMNA (0.64) | MAPTMEN1KMT2ATSHRTAAR1 | |
| SCHEMBL468013 | 0.80 | MEN1 (0.58) | GAAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989131-B | N' - (2- (benzo [1,3] dioxolan-5-yl) acyl) aryl hydrazide compound as well as synthesis and application thereof | 云南大学 | 2023-10-24 | — | — | CN | disclosed |
| EP-3634406-B1 | 3,4,5-TRISUBSTITUTED-1,2,4-TRIAZOLES AND 3,4,5-TRISUBSTITUTED-3-THIO-1,2,4-TRIAZOLES AND USES THEREOF | BOARD OF TRUSTEES OF THE SOUTHERN ILLINOIS UNIV ON BEHALF OF SOUTHERN ILLINOIS UNIV EDWARDSVILLE (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-114989131-A | N' - (2- (benzo [1,3] dioxolane-5-yl) acyl) aroyl hydrazide compound and synthesis and application thereof | 云南大学 | 2022-09-02 | — | — | CN | disclosed |