Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | AOC2 | O75106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8838392 | 0.83 | L3MBTL1 (0.53) | MAPK8L3MBTL1GLSHTTKMT2A | |
| SCHEMBL968090 | 0.83 | POLB (0.59) | MAPK8GLSHTTKMT2APOLB | |
| SCHEMBL29664449 | 0.82 | L3MBTL1 (0.49) | MAPK8L3MBTL1GLSHTTKMT2A | |
| SCHEMBL2494898 | 0.81 | HTT (0.73) | MAPK8HTTKMT2ACA1CA2 | |
| SCHEMBL2847513 | 0.79 | MAPK8 (0.50) | MAPK8L3MBTL1GLSKMT2APOLB | |
| SCHEMBL348963 | 0.79 | HSP90AB1 (0.62) | MAPK8L3MBTL1GLSKMT2APOLB | |
| SCHEMBL26414135 | 0.78 | L3MBTL1 (0.46) | MAPK8L3MBTL1KMT2APOLBSIGMAR1 | |
| SCHEMBL17730733 | 0.77 | CACNA1H (0.44) | HTTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL347352 | 0.76 | PTGS1 (0.59) | L3MBTL1KMT2APOLBKDM4EGAA | |
| SCHEMBL1162659 | 0.76 | ALDH1A1 (0.48) | MAPK8L3MBTL1GLSKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989131-B | N' - (2- (benzo [1,3] dioxolan-5-yl) acyl) aryl hydrazide compound as well as synthesis and application thereof | 云南大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-114989131-A | N' - (2- (benzo [1,3] dioxolane-5-yl) acyl) aroyl hydrazide compound and synthesis and application thereof | 云南大学 | 2022-09-02 | — | — | CN | disclosed |