Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19133623 | 0.83 | CA1 (0.59) | L3MBTL1CA1CA2POLBSMN1; SMN2 | |
| SCHEMBL29907960 | 0.82 | MAPK8 (0.54) | L3MBTL1CA1CA2MAPK8GLS | |
| SCHEMBL8838392 | 0.80 | L3MBTL1 (0.53) | L3MBTL1MAPK8GLSHTTKMT2A | |
| SCHEMBL28706052 | 0.79 | LMNA (0.49) | L3MBTL1CA1CA2HTTKMT2A | |
| SCHEMBL13543196 | 0.77 | CYP24A1 (0.50) | L3MBTL1MAPK8GLSKMT2APOLB | |
| SCHEMBL348963 | 0.76 | HSP90AB1 (0.62) | L3MBTL1MAPK8GLSKMT2APOLB | |
| SCHEMBL21672231 | 0.75 | KMT2A (0.53) | L3MBTL1CA1CA2MAPK8KMT2A | |
| SCHEMBL11763680 | 0.75 | HTT (0.45) | L3MBTL1MAPK8GLSHTTKMT2A | |
| SCHEMBL2552724 | 0.74 | MTNR1A (0.48) | L3MBTL1MAPK8GLSKMT2APOLB | |
| SCHEMBL1162659 | 0.74 | ALDH1A1 (0.48) | L3MBTL1MAPK8GLSKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539100-A | Terbutaline derivative D and preparation method and application thereof | 嘉实（湖南）医药科技有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114539100-A | Terbutaline derivative D and preparation method and application thereof | 嘉实（湖南）医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |