Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576801 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TP53MTNR1AMTNR1BCYP2A6 | |
| SCHEMBL23578008 | 0.91 | TP53 (0.36) | ALDH1A1TP53MTNR1AMTNR1BKMT2A | |
| SCHEMBL29909352 | 0.91 | TP53 (0.36) | ALDH1A1TP53MTNR1AMTNR1BKMT2A | |
| SCHEMBL29909317 | 0.90 | DHODH (0.33) | ALDH1A1CYP2A6MEN1KMT2AMAPT | |
| SCHEMBL23576639 | 0.90 | DHODH (0.33) | ALDH1A1CYP2A6MEN1KMT2AMAPT | |
| SCHEMBL23576641 | 0.89 | FNTA (0.35) | ALDH1A1TP53MAPTPTGER4 | |
| SCHEMBL29909377 | 0.89 | FNTA (0.35) | ALDH1A1TP53MAPTPTGER4 | |
| SCHEMBL23577116 | 0.88 | ASIC1 (0.33) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL29909022 | 0.88 | ASIC1 (0.33) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL24721227 | 0.87 | TP53 (0.41) | ALDH1A1TP53KMT2AMAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |