Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578008 | 1.00 | TP53 (0.36) | TP53MAPTALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL23576801 | 0.91 | ALDH1A1 (0.36) | TP53MAPTALDH1A1EGFRPDGFRB | |
| SCHEMBL29909055 | 0.91 | ALDH1A1 (0.36) | TP53MAPTALDH1A1EGFRPDGFRB | |
| SCHEMBL29909268 | 0.90 | MAPT (0.32) | MAPTALDH1A1 | |
| SCHEMBL23576867 | 0.90 | MAPT (0.32) | MAPTALDH1A1 | |
| SCHEMBL23577570 | 0.89 | FNTA (0.35) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL29909418 | 0.89 | FNTA (0.35) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL23576883 | 0.88 | ASIC1 (0.33) | — | |
| SCHEMBL29909412 | 0.88 | ASIC1 (0.33) | — | |
| SCHEMBL24721227 | 0.87 | TP53 (0.41) | TP53MAPTALDH1A1EGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |