Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576641 | 1.00 | FNTA (0.35) | FNTAFNTBMAPTPOLBTP53 | |
| SCHEMBL23576639 | 0.92 | DHODH (0.33) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29909317 | 0.92 | DHODH (0.33) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29909418 | 0.91 | FNTA (0.35) | FNTAFNTBMAPTPOLBTP53 | |
| SCHEMBL23577570 | 0.91 | FNTA (0.35) | FNTAFNTBMAPTPOLBTP53 | |
| SCHEMBL23601235 | 0.89 | FNTA (0.40) | FNTAFNTBMAPTPOLBTP53 | |
| SCHEMBL29909768 | 0.89 | FNTA (0.40) | FNTAFNTBMAPTPOLBTP53 | |
| SCHEMBL23577116 | 0.89 | ASIC1 (0.33) | FNTAFNTBMAPTKDM4EALDH1A1 | |
| SCHEMBL23576801 | 0.89 | ALDH1A1 (0.36) | MAPTTP53ALDH1A1PTGER4 | |
| SCHEMBL29909055 | 0.89 | ALDH1A1 (0.36) | MAPTTP53ALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |