Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | DHODH | Q02127 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577369 | 1.00 | EGFR (0.36) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL29909030 | 0.85 | KDM4E (0.33) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24816016 | 0.84 | DHODH (0.36) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL30047500 | 0.83 | EGFR (0.37) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL24814725 | 0.83 | EGFR (0.37) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL23601562 | 0.81 | TUBB4A (0.44) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL29909744 | 0.81 | TUBB4A (0.44) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL30047399 | 0.78 | CYP1A2 (0.39) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL24814614 | 0.78 | CYP1A2 (0.39) | EGFRTUBB4ATUBBPDGFRBTUBA3C | |
| SCHEMBL23601370 | 0.76 | HTR6 (0.33) | SMN1; SMN2HTTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |