SCHEMBL29909628

SCHEMBL29909628

CN(c1cc(F)cc(Br)c1)c1nc2nncn2c2cc(C(F)(F)F)ccc12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576663 1.00 KIF11 (0.30) KIF11
SCHEMBL23601650 0.89 MAPT (0.31) KIF11
SCHEMBL29909100 0.86 MAT2A (0.35)
SCHEMBL23576693 0.86 MAT2A (0.35)
SCHEMBL29909658 0.83 NCEH1 (0.32)
SCHEMBL23577271 0.83 NCEH1 (0.32)
SCHEMBL29909212 0.83 KIF11 (0.39) KIF11
SCHEMBL23577152 0.83 KIF11 (0.39) KIF11
SCHEMBL30013722 0.82 CSNK2A1 (0.36)
SCHEMBL23577324 0.82 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed