Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601353 | 0.89 | KMT2A (0.38) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23576663 | 0.89 | KIF11 (0.30) | KIF11 | |
| SCHEMBL29909628 | 0.89 | KIF11 (0.30) | KIF11 | |
| SCHEMBL23601004 | 0.85 | MAT2A (0.36) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL29909212 | 0.84 | KIF11 (0.39) | MAPTSMN1; SMN2KIF11 | |
| SCHEMBL23577152 | 0.84 | KIF11 (0.39) | MAPTSMN1; SMN2KIF11 | |
| SCHEMBL23601007 | 0.82 | MAPT (0.36) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23576803 | 0.81 | — | — | |
| SCHEMBL29909125 | 0.81 | — | — | |
| SCHEMBL29909303 | 0.79 | CYP11B2 (0.32) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |