Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577324 | 1.00 | MAPT (0.33) | MAPTSMN1; SMN2ABCG2HTR6MEN1 | |
| SCHEMBL23601024 | 0.88 | ABCG2 (0.38) | MAPTSMN1; SMN2ABCG2 | |
| SCHEMBL23601007 | 0.88 | MAPT (0.36) | MAPTSMN1; SMN2ABCG2MEN1POLB | |
| SCHEMBL29909847 | 0.84 | — | — | |
| SCHEMBL29909100 | 0.84 | MAT2A (0.35) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23576693 | 0.84 | MAT2A (0.35) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23577456 | 0.84 | — | — | |
| SCHEMBL23578049 | 0.84 | ABCG2 (0.42) | SMN1; SMN2ABCG2 | |
| SCHEMBL23577671 | 0.83 | HTR6 (0.32) | MAPTHTR6 | |
| SCHEMBL29909064 | 0.83 | HTR6 (0.32) | MAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |