Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577671 | 1.00 | HTR6 (0.32) | HTR6MAPTPER2CRY1CRY2 | |
| SCHEMBL29909815 | 0.83 | MAPT (0.33) | HTR6MAPT | |
| SCHEMBL23577324 | 0.83 | MAPT (0.33) | HTR6MAPT | |
| SCHEMBL29909810 | 0.80 | TNIK (0.33) | PER2CRY1CRY2 | |
| SCHEMBL23601998 | 0.80 | TNIK (0.33) | PER2CRY1CRY2 | |
| SCHEMBL23601256 | 0.80 | PER2 (0.31) | PER2CRY1CRY2 | |
| SCHEMBL23601258 | 0.80 | — | — | |
| SCHEMBL29909040 | 0.79 | PER2 (0.32) | PER2CRY1CRY2 | |
| SCHEMBL23601024 | 0.74 | ABCG2 (0.38) | MAPT | |
| SCHEMBL23576680 | 0.73 | HTT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |