Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710410 | 1.00 | GLS (0.52) | GLSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4837787 | 0.90 | GLS (0.54) | GLSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4709921 | 0.89 | GLS (0.52) | GLSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL13236926 | 0.88 | GLS (0.54) | GLSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2236220 | 0.87 | VEGFA (0.54) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL24732680 | 0.86 | PRMT6 (0.54) | GLSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16855800 | 0.86 | GLS (0.53) | GLSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2194827 | 0.85 | KDM1A (0.57) | GLSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8540779 | 0.85 | ALDH1A1 (0.63) | GLSCHRM2CHRM3ALDH1A1HTT | |
| SCHEMBL13761240 | 0.84 | GLS (0.49) | GLSCHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054724-A1 | BIFUNCTIONAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2022-09-14 | — | — | EP | disclosed |