Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.41 |
| ▸ | HTR2A | P28223 | 10/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452521 | 1.00 | SLC6A4 (0.41) | SLC6A4HTR2ARIPK1KCNH2CHRM4 | |
| SCHEMBL29912873 | 0.79 | RIPK1 (0.40) | SLC6A4HTR2ARIPK1CHRM4ROCK2 | |
| SCHEMBL12640806 | 0.79 | RIPK1 (0.40) | SLC6A4HTR2ARIPK1CHRM4ROCK2 | |
| SCHEMBL18589012 | 0.79 | SLC6A2 (0.47) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL17882408 | 0.78 | RIPK1 (0.41) | RIPK1CHRM4ROCK2ROCK1 | |
| SCHEMBL4835664 | 0.76 | GAA (0.42) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL29788838 | 0.75 | RIPK1 (0.46) | RIPK1CHRM4ROCK2ROCK1 | |
| SCHEMBL24059231 | 0.75 | ALDH1A1 (0.38) | SLC6A4HTR2ARIPK1KCNH2SLC6A2 | |
| SCHEMBL10195688 | 0.75 | RIPK1 (0.49) | RIPK1CHRM4 | |
| SCHEMBL3127209 | 0.74 | SLC6A4 (0.54) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197098-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2023-08-08 | — | — | CN | disclosed |
| CN-115197098-A | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-107108467-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-08-19 | — | — | CN | disclosed |