Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19356339 | 0.85 | SLC6A2 (0.41) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL22623063 | 0.81 | BCAT2 (0.33) | SLC6A4TAAR1MAPT | |
| SCHEMBL25376811 | 0.78 | SLC6A4 (0.36) | RAPGEF4SLC6A4HTR2AKCNH2SLC6A2 | |
| SCHEMBL18803854 | 0.77 | ALDH1A1 (0.36) | ALDH1A1RAPGEF4RIPK1STIM1ORAI1 | |
| SCHEMBL2091126 | 0.75 | GPR84 (0.38) | ALDH1A1RAPGEF4RIPK1TAAR1GPR84 | |
| SCHEMBL6072037 | 0.75 | TAAR1 (0.43) | ALDH1A1TAAR1GPR84KDM4EMEN1 | |
| SCHEMBL13452521 | 0.75 | SLC6A4 (0.41) | SLC6A4HTR2ARIPK1KCNH2SLC6A2 | |
| SCHEMBL29912949 | 0.75 | SLC6A4 (0.41) | SLC6A4HTR2ARIPK1KCNH2SLC6A2 | |
| SCHEMBL22482741 | 0.75 | ALDH1A1 (0.36) | ALDH1A1RAPGEF4RIPK1STIM1ORAI1 | |
| Hydrochloric Acid SCHEMBL29210672 | 0.73 | KDM4E (0.44) | ALDH1A1TAAR1GPR84KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677598-B | Preparation method for synthesizing pyrimidinedione compound | 南通常佑药业科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| US-12037343-B2 | Process for the preparation of sodium (2r,5s,13ar)-7,9-dioxo-10-((2,4,6,-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13A-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-B] [1,3] oxazepin-8-olate and its polymorphic form | HONOUR LAB LIMITED (IN) | 2024-07-16 | — | — | US | disclosed |
| US-20230219977-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | HONOUR LAB LIMITED (IN) | 2023-07-13 | — | — | US | disclosed |
| WO-2022258052-A1 | HETEROCYCLIC LACTAM COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-12-15 | — | — | WO | disclosed |
| US-20210363158-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | HONOUR LAB LIMITED (IN) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363158-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | OXER1, CYP4Z1, CYP4A11 | ALDH1A1 671/4885RAPGEF4 2233/4885SLC6A4 906/4885 |
| US-12037343-B2 | Process for the preparation of sodium (2r,5s,13ar)-7,9-dioxo-10-((2,4,6,-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13A-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-B] [1,3] oxazepin-8-olate and its polymorphic form | OXER1, OR10J3, CYP2A13 | ALDH1A1 577/4885RAPGEF4 2073/4885SLC6A4 1134/4885 |
| US-20230219977-A1 | PROCESS FOR THE PREPARATION OF SODIUM (2R,5S,13AR)-7,9-DIOXO-10-((2,4,6-TRIFLUOROBENZYL)CARBAMOYL)-2,3,4,5,7,9,13,13A-OCTAHYDRO-2,5-METHANOPYRIDO[1',2':4,5]PYRAZINO[2,1-B] [1,3] OXAZEPIN-8-OLATE AND ITS POLYMORPHIC FORM | OXER1, CYP26B1, OR10J3 | ALDH1A1 777/4885RAPGEF4 2337/4885SLC6A4 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.