Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | DHODH | Q02127 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371972 | 0.83 | SMN1; SMN2 (0.52) | MAPTKDM4ENPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3370278 | 0.82 | TRPM8 (0.58) | CDC7DBF4MAPTKDM4EALDH1A1 | |
| SCHEMBL299133 | 0.82 | LMNA (0.63) | CDC7DBF4MAPTKDM4EDHODH | |
| SCHEMBL4464882 | 0.81 | CDC7 (0.73) | CDC7DBF4MAPTKDM4EDHODH | |
| SCHEMBL455876 | 0.81 | CDC7 (0.62) | CDC7DBF4MAPTKDM4EDHODH | |
| SCHEMBL12186978 | 0.78 | CDC7 (0.64) | CDC7DBF4MAPTKDM4EDHODH | |
| SCHEMBL289602 | 0.78 | KDM4E (0.62) | CDC7DBF4MAPTKDM4EDHODH | |
| SCHEMBL12034449 | 0.77 | CDC7 (0.69) | CDC7DBF4MAPTKDM4ENPSR1 | |
| SCHEMBL290384 | 0.77 | CDC7 (0.75) | CDC7DBF4MAPTKDM4EALDH1A1 | |
| SCHEMBL14109861 | 0.76 | KDM4E (0.60) | CDC7DBF4MAPTKDM4EDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |