Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | P4HB | P07237 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxazorone SCHEMBL2109280 | 1.00 | TDP1 (0.66) | TDP1POLBKDM4EGAAHSD17B10 | |
| SCHEMBL28167086 | 0.87 | TDP1 (0.68) | TDP1POLBKDM4EGAAHSD17B10 | |
| Folescutol SCHEMBL554577 | 0.84 | TDP1 (0.81) | TDP1POLBKDM4EGAAHSD17B10 | |
| SCHEMBL30507291 | 0.82 | ALDH1A1 (0.70) | TDP1POLBKDM4EGAAHSD17B10 | |
| SCHEMBL24589796 | 0.79 | KMT2A (0.66) | TDP1POLBKDM4EGAAHSD17B10 | |
| SCHEMBL3252425 | 0.78 | SIGMAR1 (0.50) | TDP1POLBKDM4EGAAHSD17B10 | |
| SCHEMBL27757150 | 0.77 | HSD17B3 (0.73) | KDM4EGAAHSD17B10KMT2AALDH1A1 | |
| SCHEMBL13851555 | 0.77 | HSD17B3 (0.64) | TDP1KDM4EGAAHSD17B10KMT2A | |
| SCHEMBL28499055 | 0.77 | PRKDC (0.68) | KDM4EGAAHSD17B10KMT2AALDH1A1 | |
| SCHEMBL26770692 | 0.76 | PDE2A (0.57) | KDM4EGAAHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115023222-A | Treatment of neurological disorders | J·夸克 | 2022-09-06 | — | — | CN | disclosed |