Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706650 | 1.00 | NPC1 (0.54) | NPC1RAB9AMAPTPTGS2MAOB | |
| SCHEMBL6706648 | 1.00 | NPC1 (0.54) | NPC1RAB9AMAPTPTGS2MAOB | |
| SCHEMBL19747119 | 0.81 | TPH1 (0.43) | NPC1RAB9AMAPT | |
| SCHEMBL4413540 | 0.81 | TAS1R3 (0.47) | NPC1RAB9AMAPTPTGS2MAOB | |
| SCHEMBL4993805 | 0.81 | TAS1R3 (0.47) | NPC1RAB9AMAPTPTGS2MAOB | |
| SCHEMBL13144734 | 0.80 | MAOB (0.51) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL8535983 | 0.77 | MAOB (0.59) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL30795393 | 0.77 | MAOA (0.56) | NPC1RAB9AMAPTMAOBMAOA | |
| SCHEMBL7023745 | 0.77 | TAS1R3 (0.60) | NPC1RAB9AMAPTPTGS2MAOB | |
| SCHEMBL18642545 | 0.76 | JAK2 (0.43) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395553-A1 | CXCR4 ANTAGONIST PEPTIDES | COHBAR, INC. | 2022-12-15 | — | — | US | disclosed |
| US-20220324909-A1 | THERAPEUTIC PEPTIDES | COHBAR, INC. | 2022-10-13 | — | — | US | disclosed |