Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 2/20 | 0.55 |
| ▸ | PLAU | P00749 | 5/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | SDHB | P21912 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 2/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507787 | 1.00 | CA12 (0.59) | CA12CA9CA1CA2PDK2 | |
| SCHEMBL7824610 | 0.89 | PDK2 (0.54) | CA12CA9CA1CA2PDK2 | |
| SCHEMBL8442634 | 0.88 | ERN1 (0.53) | CA12CA9CA1CA2PDK2 | |
| SCHEMBL27715902 | 0.85 | CA12 (0.71) | CA12CA9CA1CA2ERN1 | |
| SCHEMBL9798788 | 0.85 | PLAU (0.58) | CA12CA9CA1CA2PDK2 | |
| SCHEMBL68931 | 0.84 | CA12 (0.69) | CA12CA9CA1CA2ERN1 | |
| SCHEMBL13063663 | 0.84 | LMNA (0.56) | CA12CA9CA1CA2KIF11 | |
| SCHEMBL2271347 | 0.84 | LMNA (0.56) | CA12CA9CA1CA2KIF11 | |
| SCHEMBL67941 | 0.83 | CA12 (0.68) | CA12CA9CA1CA2PDK2 | |
| Trifluoroacetic Acid SCHEMBL27749215 | 0.83 | PDK2 (0.57) | CA12CA9CA1CA2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978200-B | Biphenylamide derivative, preparation method and application | 湖北省生物农药工程研究中心 | 2022-09-13 | — | — | CN | disclosed |