Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892250 | 0.75 | — | — | |
| SCHEMBL273463 | 0.74 | — | — | |
| SCHEMBL10681570 | 0.70 | CYP2E1 (0.36) | CYP2E1CYP3A4CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL14189540 | 0.69 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2CYP3A4PARP15 | |
| SCHEMBL31206750 | 0.69 | HCAR2 (0.43) | RAB9ANPC1SMN1; SMN2CYP2E1CYP3A4 | |
| SCHEMBL16887640 | 0.68 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2PARP15PARP10 | |
| SCHEMBL2149970 | 0.68 | CYP2C19 (0.47) | RAB9ANPC1SMN1; SMN2CYP2C19TDP1 | |
| SCHEMBL19475116 | 0.67 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2PARP15PARP10 | |
| SCHEMBL16886384 | 0.67 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2PARP15PARP10 | |
| SCHEMBL9481 | 0.66 | CTSK (0.43) | RAB9ANPC1SMN1; SMN2PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612374-B2 | Thiazole and diphenyl substituted sulfoxides for use in improving cognition functions and against addictions to substances | COGMOTIV FLEXCO (AT) | 2026-04-28 | — | — | US | disclosed |
| US-20220324821-A1 | THIAZOLE AND DIPHENYL SUBSTITUTED SULFOXIDES FOR USE IN IMPROVING COGNITION FUNCTIONS AND AGAINST ADDICTIONS TO SUBSTANCES | COGMOTIV FLEXCO (AT) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612374-B2 | Thiazole and diphenyl substituted sulfoxides for use in improving cognition functions and against addictions to substances | CHAT, PNMT, CHRM5 | RAB9A 2560/4885NPC1 3084/4885SMN1; SMN2 483/4885 |
| US-20220324821-A1 | THIAZOLE AND DIPHENYL SUBSTITUTED SULFOXIDES FOR USE IN IMPROVING COGNITION FUNCTIONS AND AGAINST ADDICTIONS TO SUBSTANCES | COMT, TST, PNMT | RAB9A 1634/4885NPC1 1758/4885SMN1; SMN2 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.