Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920502 | 1.00 | CA2 (0.43) | CA2AKR1B1KCNE1KCNQ1HTR2A | |
| SCHEMBL29920312 | 0.74 | TRPV1 (0.43) | KCNE1KCNQ1 | |
| SCHEMBL29920334 | 0.74 | TRPV1 (0.43) | KCNE1KCNQ1 | |
| SCHEMBL29920568 | 0.72 | PSEN1 (0.35) | CA2KCNE1KCNQ1HTR2AHTR2C | |
| SCHEMBL29920475 | 0.72 | PSEN1 (0.35) | CA2KCNE1KCNQ1HTR2AHTR2C | |
| SCHEMBL29920313 | 0.72 | PSEN1 (0.35) | CA2KCNE1KCNQ1HTR2AHTR2C | |
| SCHEMBL29920403 | 0.70 | LTB4R (0.44) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920554 | 0.70 | LTB4R (0.44) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920748 | 0.70 | TRPV1 (0.38) | CA2KCNE1KCNQ1PSEN1PSEN2 | |
| SCHEMBL29920373 | 0.70 | TRPV1 (0.38) | CA2KCNE1KCNQ1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |