Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 15/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920554 | 1.00 | LTB4R (0.44) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL29920646 | 0.76 | CA2 (0.43) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL29920642 | 0.76 | CA2 (0.43) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL29920290 | 0.73 | CA2 (0.38) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL29920682 | 0.73 | CA2 (0.38) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL29920587 | 0.70 | CA2 (0.32) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL29920659 | 0.70 | CA2 (0.32) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL29920510 | 0.70 | CA2 (0.32) | LTB4RLTB4R2CA2NR3C1NR3C2 | |
| SCHEMBL12237084 | 0.67 | LTB4R (0.47) | LTB4RLTB4R2 | |
| SCHEMBL14376996 | 0.67 | LTB4R (0.47) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |