Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 11/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 12/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178321 | 1.00 | MAOA (0.56) | MAOAMAOBNISCHADRA2CADRA2B | |
| SCHEMBL11259524 | 0.87 | MAOA (0.60) | MAOAMAOBNISCHADRA2CADRA2B | |
| Hydrochloric Acid SCHEMBL11254132 | 0.86 | MAOA (0.59) | MAOAMAOBNISCHADRA2CADRA2B | |
| SCHEMBL3172126 | 0.81 | MAOA (0.56) | MAOAMAOBNISCHADRA2CADRA2B | |
| SCHEMBL3173010 | 0.79 | MAOA (0.71) | MAOAMAOBNISCHADRA2CADRA2B | |
| SCHEMBL3169152 | 0.77 | MAOA (0.68) | MAOAMAOBNISCHADRA2CADRA2B | |
| SCHEMBL18136160 | 0.73 | MAOA (0.57) | MAOAMAOBNISCHADRA2CADRA2B | |
| SCHEMBL15378775 | 0.73 | MAOA (0.57) | MAOAMAOBNISCHADRA2CADRA2B | |
| SCHEMBL18330525 | 0.73 | MAOA (0.71) | MAOAMAOBNISCHADRA2CADRA2B | |
| Phenamazoline SCHEMBL936813 | 0.72 | MAOA (1.00) | MAOAMAOBNISCHADRA2CADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220280527-A1 | TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT | PURDUE PHARMA L.P. (US) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220280527-A1 | TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT | TAAR1, TAAR5, OPRL1 | MAOA 360/4885MAOB 454/4885NISCH 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.