Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16064982 | 0.82 | OPRM1 (0.46) | OPRM1OPRD1CA1CA2CA4 | |
| SCHEMBL29922012 | 0.79 | POLB (0.42) | OPRM1OPRD1PDK2PTGS2S100A4 | |
| SCHEMBL7697104 | 0.76 | CFTR (0.50) | CA1CA2CA7CA9AKR1C1 | |
| SCHEMBL29618362 | 0.76 | PDK2 (0.53) | OPRM1OPRD1CA1CA2CA4 | |
| SCHEMBL29618364 | 0.76 | PDK2 (0.53) | OPRM1OPRD1CA1CA2CA4 | |
| SCHEMBL24517455 | 0.76 | PDK2 (0.53) | OPRM1OPRD1CA1CA2CA4 | |
| SCHEMBL29922211 | 0.75 | OPRM1 (0.46) | OPRM1OPRD1CA1CA2CA4 | |
| SCHEMBL23526283 | 0.72 | PDK2 (0.42) | OPRM1OPRD1CA1CA2CA4 | |
| SCHEMBL29275490 | 0.71 | S100A4 (0.41) | OPRM1OPRD1CA1CA2CA4 | |
| SCHEMBL2484540 | 0.71 | PDK2 (0.50) | CA1CA2CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |