Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512967 | 0.80 | MALT1 (0.43) | MALT1ALDH1A1MAPTMAOBKDM4E | |
| SCHEMBL29922056 | 0.80 | LMNA (0.53) | ALDH1A1MAPTMAOBKDM4EL3MBTL1 | |
| SCHEMBL1110064 | 0.77 | POLB (0.54) | MAPTMAOBL3MBTL1POLBLMNA | |
| SCHEMBL15724661 | 0.75 | AKR1B1 (0.46) | MALT1ALDH1A1MAPTMAOBKDM4E | |
| SCHEMBL21131588 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAOBSRD5A1CA1CA2 | |
| SCHEMBL20951663 | 0.74 | CA1 (0.43) | MALT1ALDH1A1SRD5A1CA1CA2 | |
| SCHEMBL29920457 | 0.73 | ALDH1A1 (0.67) | ALDH1A1MAPTMAOBKDM4E | |
| SCHEMBL1569957 | 0.73 | ALDH1A1 (0.67) | ALDH1A1MAPTMAOBKDM4E | |
| SCHEMBL29922163 | 0.73 | CA1 (0.42) | ALDH1A1MAPTMAOBKDM4ECA1 | |
| SCHEMBL9220704 | 0.72 | AKR1B1 (0.42) | MALT1ALDH1A1MAPTMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |