Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922140 | 0.80 | MALT1 (0.43) | MALT1MAOBKDM4EALDH1A1AVPR1A | |
| SCHEMBL29922056 | 0.80 | LMNA (0.53) | TDP2MAOBKDM4EALDH1A1S100A4 | |
| SCHEMBL1110064 | 0.77 | POLB (0.54) | MAOBUTS2RMAPTL3MBTL1POLB | |
| SCHEMBL31185052 | 0.75 | MAPT (0.40) | MALT1MAOBKDM4EALDH1A1BRD4 | |
| SCHEMBL5269029 | 0.75 | MAPT (0.40) | MALT1MAOBKDM4EALDH1A1BRD4 | |
| SCHEMBL1500161 | 0.74 | TDP2 (0.46) | MALT1TDP2METAP1ALDH1A1PARP10 | |
| SCHEMBL6552997 | 0.73 | ALDH1A1 (0.67) | MALT1MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL29640611 | 0.73 | ALDH1A1 (0.67) | MALT1MAOBKDM4EALDH1A1MAPT | |
| SCHEMBL29922163 | 0.73 | CA1 (0.42) | MAOBKDM4EALDH1A1MAPTCA1 | |
| SCHEMBL13950513 | 0.72 | TDP2 (0.45) | TDP2METAP1KDM4EALDH1A1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |