Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390689 | 0.85 | ACHE (0.46) | CA1CA2CA7CA9SRD5A1 | |
| SCHEMBL9589413 | 0.82 | SRD5A1 (0.45) | CA1CA2CA7CA9SRD5A1 | |
| SCHEMBL10908106 | 0.82 | CA1 (0.41) | CA1CA2CA7CA9SRD5A1 | |
| SCHEMBL5288032 | 0.80 | MAPK14 (0.56) | ALDH1A1 | |
| SCHEMBL5320166 | 0.80 | TDP2 (0.33) | CA1CA2CA7CA9GRM1 | |
| SCHEMBL12310527 | 0.79 | METAP1 (0.44) | CA1CA2CA7CA9SRD5A1 | |
| SCHEMBL5293741 | 0.78 | MAPK14 (0.58) | — | |
| SCHEMBL1500161 | 0.78 | TDP2 (0.46) | CA1CA2CA7CA9SRD5A1 | |
| SCHEMBL20950906 | 0.78 | CASP1 (0.47) | CA9GRM1ALDH1A1TDP2PARP1 | |
| SCHEMBL21131588 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA7CA9SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052863-B | Azole derivative, process for producing azole derivative, agricultural/horticultural agent, and industrial material protective agent | 株式会社吴羽 | 2023-04-28 | — | — | CN | disclosed |
| CN-115052863-A | Azole derivative, process for producing azole derivative, and agricultural and horticultural chemical agent and industrial material protective agent | 株式会社吴羽 | 2022-09-13 | — | — | CN | disclosed |
| EP-3447045-B9 | 1-(1-HYDROXY-2,3-DIHYDRO-1H-INDEN-5-YL)-UREA DERIVATIVES AND RELATED COMPOUNDS KCNQ 2-5 CHANNEL ACTIVATORS FOR TREATING DYSURIA | ONO PHARMACEUTICAL CO (JP) | 2021-07-21 | — | — | EP | disclosed |
| EP-3447045-B1 | 1-(1-HYDROXY-2,3-DIHYDRO-1H-INDEN-5-YL)-UREA DERIVATIVES AND RELATED COMPOUNDS KCNQ 2-5 CHANNEL ACTIVATORS FOR TREATING DYSURIA | ONO PHARMACEUTICAL CO (JP) | 2021-03-03 | — | — | EP | disclosed |
| US-20190127320-A1 | KCNQ2-5 CHANNEL ACTIVATOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127320-A1 | KCNQ2-5 CHANNEL ACTIVATOR | KCNQ5, KCNQ2, KCNQ1 | CA1 2732/4885CA2 501/4885CA7 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.