Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362527 | 1.00 | L3MBTL1 (0.42) | L3MBTL1SLC6A2SLC6A4SYKPDE7A | |
| SCHEMBL29552160 | 0.90 | L3MBTL1 (0.46) | L3MBTL1SLC6A2SLC6A4SYKPDE7A | |
| SCHEMBL28359081 | 0.87 | SYK (0.35) | SYKPDE7APTGS2ATMKMT2A | |
| SCHEMBL29922584 | 0.87 | SYK (0.35) | SYKPDE7APTGS2ATMKMT2A | |
| SCHEMBL29922837 | 0.83 | TYK2 (0.56) | L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL28359224 | 0.83 | TYK2 (0.56) | L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL29922581 | 0.78 | JAK2 (0.52) | L3MBTL1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28359240 | 0.78 | JAK2 (0.52) | L3MBTL1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15091096 | 0.75 | SYK (0.56) | L3MBTL1SYKGFERKMT2AMAPT | |
| SCHEMBL29922724 | 0.75 | SYK (0.46) | L3MBTL1SYKKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |