Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | METAP1 | P53582 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345374 | 0.72 | ACHE (0.55) | ACHEMETAP1CYP19A1SIGMAR1 | |
| SCHEMBL30785363 | 0.72 | ACHE (0.55) | ACHEMETAP1CYP19A1SIGMAR1 | |
| SCHEMBL29922862 | 0.71 | KDM4E (0.44) | ACHEMAOAMAOBPTGS2KDM4E | |
| SCHEMBL16393588 | 0.71 | KDM4E (0.44) | ACHEMAOAMAOBPTGS2KDM4E | |
| SCHEMBL2920960 | 0.70 | CYP19A1 (0.56) | ACHEMETAP1CYP19A1MAOBKDM4E | |
| Benzene SCHEMBL28074857 | 0.70 | KDM4E (0.42) | ACHEMAOAMAOBPTGS2KDM4E | |
| SCHEMBL7118363 | 0.67 | ADRA1A (0.43) | SIGMAR1 | |
| SCHEMBL8001882 | 0.67 | RAB9A (0.53) | ACHEMETAP1CYP19A1SIGMAR1KDM4E | |
| SCHEMBL13176510 | 0.67 | KDM4E (0.53) | ACHEMETAP1CYP19A1KDM4EL3MBTL1 | |
| SCHEMBL19748752 | 0.67 | CYP19A1 (0.56) | ACHEMETAP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433021-B1 | ANTIINFLAMMATORY AGENTS; MAST CELL STABILIZERS | VENANTIUS LIMITED (IL) | 2002-08-13 | — | — | US | disclosed |