Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 11/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922801 | 0.89 | RAB9A (0.54) | NPC1RAB9ADGAT1CNR2KCNQ3 | |
| SCHEMBL29922727 | 0.83 | JAK2 (0.55) | DGAT1KDM4EGAAMAPTLMNA | |
| SCHEMBL29923134 | 0.81 | TYK2 (0.56) | NPC1RAB9ADGAT1CNR2KCNQ3 | |
| SCHEMBL28358972 | 0.81 | TYK2 (0.56) | NPC1RAB9ADGAT1CNR2KCNQ3 | |
| SCHEMBL29552247 | 0.81 | TYK2 (0.56) | NPC1RAB9ADGAT1CNR2KCNQ3 | |
| SCHEMBL29922709 | 0.76 | KDR (0.41) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL29922857 | 0.75 | MAPT (0.37) | KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL29923095 | 0.73 | JAK2 (0.66) | — | |
| SCHEMBL29922578 | 0.72 | TYK2 (0.58) | DGAT1CNR2 | |
| SCHEMBL16362450 | 0.72 | JAK2 (0.56) | NPC1RAB9ADGAT1CNR2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |