Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732753 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL2791334 | 0.88 | GPR27 (0.42) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL12198248 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL12677014 | 0.83 | TSHR (0.47) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL4403107 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL29923705 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2TSHRALDH1A1KDM4ESORT1 | |
| SCHEMBL6728055 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2TSHRALDH1A1KDM4ESORT1 | |
| SCHEMBL10575131 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL7910265 | 0.80 | HTT (0.47) | SMN1; SMN2TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL14436800 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRMAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028596-B | Method for preparing topramezone intermediate | 帕潘纳(北京)科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115028596-A | Process for preparing topramezone intermediates | 帕潘纳(北京)科技有限公司 | 2022-09-09 | — | — | CN | disclosed |