Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923391 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL2791334 | 0.88 | GPR27 (0.42) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL12198248 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL12677014 | 0.83 | TSHR (0.47) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL4403107 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL29923705 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2TSHRALDH1A1KDM4ESORT1 | |
| SCHEMBL6728055 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2TSHRALDH1A1KDM4ESORT1 | |
| SCHEMBL10575131 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2GPR27TSHRMAPK1ALDH1A1 | |
| SCHEMBL7910265 | 0.80 | HTT (0.47) | SMN1; SMN2TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL14436800 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRMAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886218-A | REACTING 3,4-DICHLOROTOLUENE WITH ACETYL CHLORIDE OR CHLOROACETYL CHLORIDE USING A FRIEDEL-CRAFTS CATALYST; OXIDIZING THE ACETYLATED INTERMEDIATE IN THE PRESENCE OF AN ALKALI TO PRODUCE THE SALT SUBSEQUENTLY HYDROLYZED | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | claimed |
| WO-2021118171-A1 | (ARYLOXY)ALKYL GROUP-SUBSTITUTED COMPOUND AND ORGANIC ELECTRONIC DEVICE USING SAME | 경상국립대학교산학협력단 | 2021-06-17 | — | — | WO | disclosed |
| US-6677460-B1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2002-09-19 | — | — | US | disclosed |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| US-6136755-A | HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6103668-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-6063936-A | CARBOXY SUBSTITUTED BENZOTHIOPHENES USED AS HERBICIDE | IDEMITSU KOSAN CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5886218-A | REACTING 3,4-DICHLOROTOLUENE WITH ACETYL CHLORIDE OR CHLOROACETYL CHLORIDE USING A FRIEDEL-CRAFTS CATALYST; OXIDIZING THE ACETYLATED INTERMEDIATE IN THE PRESENCE OF AN ALKALI TO PRODUCE THE SALT SUBSEQUENTLY HYDROLYZED | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| US-5767289-A | HERBICIDE INTERMEDIATES | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0810226-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0805140-A1 | Process for producing 4,5-dichloro-2-methylbenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-05 | — | — | EP | disclosed |
| US-5607898-A | HERBICIDES | IDEMITSU KOSAN COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-4045169-A | FLUORESCENT DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |
| US-3957815-A | 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | XDH, SULT2A1, NAT1 | SMN1; SMN2 3397/4885GPR27 1388/4885TSHR 3347/4885 |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | SMN1; SMN2 3397/4885GPR27 1388/4885TSHR 3347/4885 |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | SMN1; SMN2 3397/4885GPR27 1388/4885TSHR 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.