Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916118 | 1.00 | PLA2G2A (0.53) | PLA2G2ABACE1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL16832843 | 0.84 | PLA2G2A (0.69) | PLA2G2ABACE1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2910558 | 0.84 | PLA2G2A (0.54) | PLA2G2ABACE1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28130384 | 0.83 | KDM4E (0.68) | PLA2G2ABACE1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1694287 | 0.81 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL32681649 | 0.81 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL28559497 | 0.80 | PLA2G2A (0.62) | PLA2G2AKDM4EALDH1A1NPSR1MEN1 | |
| SCHEMBL13234529 | 0.79 | KCNH2 (0.51) | PLA2G2ABACE1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28491584 | 0.78 | GRM2 (0.57) | PLA2G2ABACE1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28130383 | 0.77 | PLA2G2A (0.67) | PLA2G2AKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |