Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916490 | 1.00 | NQO2 (0.43) | NQO2NSD2CASP6MEN1KMT2A | |
| SCHEMBL9073161 | 0.82 | NOS3 (0.41) | NSD2CASP6MEN1KMT2AHSP90AA1 | |
| SCHEMBL29923412 | 0.78 | PTGS2 (0.43) | NSD2CASP6MEN1KMT2AHSP90AA1 | |
| SCHEMBL24916083 | 0.78 | PTGS2 (0.43) | NSD2CASP6MEN1KMT2AHSP90AA1 | |
| SCHEMBL731409 | 0.78 | HTT (0.40) | NQO2MEN1KMT2AHSP90AA1NPC1 | |
| SCHEMBL19878145 | 0.77 | NQO2 (0.41) | NQO2MEN1KMT2ANPC1MAPT | |
| SCHEMBL24916103 | 0.75 | NOS3 (0.41) | NSD2CASP6MEN1KMT2AHSP90AA1 | |
| SCHEMBL29924149 | 0.75 | NOS3 (0.41) | NSD2CASP6MEN1KMT2AHSP90AA1 | |
| SCHEMBL21494370 | 0.75 | KDM4E (0.40) | CASP6MEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL31337072 | 0.75 | HTR1A (0.59) | NQO2NSD2CASP6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |