Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | HTR2B | P41595 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923722 | 0.76 | BRD4 (0.38) | BRD4 | |
| SCHEMBL11824656 | 0.65 | HTR2C (0.59) | HTR2CHTR2BHTR2A | |
| SCHEMBL11822500 | 0.62 | HTR2C (0.59) | HTR2CHTR2BHTR2A | |
| SCHEMBL13262199 | 0.60 | TOP1 (0.40) | — | |
| SCHEMBL6904988 | 0.60 | TRPA1 (0.38) | HTR2CHTR2BHTR2ABRD4 | |
| SCHEMBL8738571 | 0.60 | ALDH1A1 (0.35) | BRD4 | |
| SCHEMBL24451866 | 0.58 | RAD52 (0.48) | HTR2CHTR2BHTR2A | |
| SCHEMBL9261043 | 0.58 | BRD4 (0.36) | BRD4 | |
| SCHEMBL10242603 | 0.57 | TNKS2 (0.41) | — | |
| SCHEMBL12319722 | 0.57 | PARP1 (0.41) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |