Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915594 | 0.79 | MTNR1B (0.33) | MTNR1BMTNR1APDGFRBPDGFRAP2RX3 | |
| SCHEMBL21783731 | 0.79 | MTNR1B (0.47) | MTNR1BMTNR1APDGFRAMEN1CYP1A2 | |
| SCHEMBL24915897 | 0.77 | CYP1A2 (0.36) | KDM4ECYP1A2 | |
| SCHEMBL24916492 | 0.76 | CYP1A1 (0.36) | CYP1A1CYP1B1MTNR1BMTNR1APDGFRB | |
| SCHEMBL29923631 | 0.76 | CYP1A1 (0.36) | CYP1A1CYP1B1MTNR1BMTNR1APDGFRB | |
| SCHEMBL24915601 | 0.75 | ALDH1A1 (0.40) | CYP1A1CYP1B1PDGFRBPDGFRAP2RX3 | |
| SCHEMBL24916399 | 0.73 | CYP11B2 (0.49) | P2RX3P2RX2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24916018 | 0.73 | PDE10A (0.31) | — | |
| SCHEMBL24842479 | 0.69 | P2RX3 (0.40) | P2RX3P2RX2ALDH1A1MEN1CYP1A2 | |
| SCHEMBL25637103 | 0.69 | EGFR (0.32) | P2RX3P2RX2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | CYP1A1 4323/4885CYP1B1 4421/4885MTNR1B 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.