Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916004 | 0.78 | LRRK2 (0.39) | KCNH2HRH3ADRA1AHRH1ADRA1B | |
| SCHEMBL12932480 | 0.74 | HTR6 (0.57) | HTR1ASLC6A4DRD2HTR2ADRD4 | |
| Hydrochloric Acid SCHEMBL1063081 | 0.74 | HTR6 (0.59) | HTR1ASLC6A4DRD2HTR2ADRD4 | |
| SCHEMBL2358654 | 0.73 | KCNH2 (0.42) | KCNH2HRH3ADRA1AHRH1HTR1A | |
| SCHEMBL1065862 | 0.72 | CKS1B (0.51) | KCNH2ACHEMAP4K4 | |
| SCHEMBL1063036 | 0.71 | ACKR3 (0.68) | KCNH2HRH1DRD2HTR2ADRD4 | |
| SCHEMBL9755216 | 0.71 | ELANE (0.45) | KCNH2ELANEACHEDRD2DRD4 | |
| SCHEMBL3924932 | 0.70 | HTR1A (0.58) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL10615678 | 0.69 | HTR1A (0.47) | KCNH2HRH3ADRA1AHRH1ADRA1B | |
| SCHEMBL10656768 | 0.69 | HTR7 (0.62) | ADRA1AHTR1ASLC6A4DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |