Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | POLR1A | O95602 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915573 | 0.81 | KMT2A (0.43) | KMT2AMCHR1POLR1AALDH1A1KCNH2 | |
| SCHEMBL31438766 | 0.78 | KMT2A (0.53) | KMT2AMCHR1ALDH1A1KDM4EHPGD | |
| SCHEMBL29535889 | 0.75 | MCHR1 (0.50) | KMT2AMCHR1SSTR4ALDH1A1KDM4E | |
| SCHEMBL29923911 | 0.73 | NFKBIA (0.49) | KMT2AALDH1A1KDM4E | |
| SCHEMBL2015530 | 0.73 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3400415 | 0.71 | PPARA (0.53) | MCHR1HPGDS | |
| SCHEMBL14924436 | 0.71 | KMT2A (0.54) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30468945 | 0.70 | SSTR4 (0.46) | SSTR4HPGDSALDH1A1KDM4EHPGD | |
| SCHEMBL4516387 | 0.69 | ALDH1A1 (0.72) | KMT2AMCHR1ALDH1A1 | |
| SCHEMBL29363800 | 0.69 | ALDH1A1 (0.72) | KMT2AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |