Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKBIA | P25963 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SCN2B | O60939 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015530 | 0.79 | KDM4E (0.49) | NFKBIAAKR1C3AKR1C2ALDH1A1KDM4E | |
| SCHEMBL24916230 | 0.77 | SCN9A (0.36) | AKR1C3AKR1C2PTGER4ALDH1A1KDM4E | |
| SCHEMBL29923902 | 0.75 | HPGDS (0.53) | NFKBIAALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL29923203 | 0.74 | PSMD14 (0.42) | NFKBIAALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL29923773 | 0.73 | KMT2A (0.47) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL10777486 | 0.71 | SCN9A (0.52) | AKR1C3AKR1C2PTGER4ALDH1A1SMN1; SMN2 | |
| SCHEMBL16618346 | 0.70 | SCN9A (0.53) | AKR1C3AKR1C2KDM4ESCN9ASCN5A | |
| SCHEMBL28529190 | 0.69 | NFKBIA (0.50) | NFKBIAMAPT | |
| SCHEMBL363816 | 0.67 | SCN9A (0.53) | SCN9ASCN1ASCN5A | |
| SCHEMBL364291 | 0.67 | SCN9A (0.64) | SCN9ASCN2BSCN1ASCN1BSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |