Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | POLR1A | O95602 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923773 | 0.81 | KMT2A (0.47) | KMT2AMCHR1ALDH1A1POLR1AKDM4E | |
| SCHEMBL24915921 | 0.80 | MTNR1A (0.43) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24916230 | 0.76 | SCN9A (0.36) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24916058 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24915923 | 0.75 | CD38 (0.45) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24915919 | 0.72 | HPGD (0.43) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24916054 | 0.72 | HTR1B (0.41) | KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL24915560 | 0.72 | PIK3CA (0.50) | KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL31438766 | 0.72 | KMT2A (0.53) | KMT2AMCHR1ALDH1A1KDM4EHPGD | |
| SCHEMBL24915570 | 0.71 | CSNK2A2 (0.39) | KMT2AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | KMT2A 641/4885MCHR1 3849/4885ALDH1A1 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.