Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22750299 | 1.00 | CRHR1 (0.47) | CRHR1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL20867656 | 0.83 | MAPT (0.50) | CRHR1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL20521814 | 0.80 | CYP3A4 (0.44) | CRHR1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL20521940 | 0.80 | KMT2A (0.44) | CRHR1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL24915974 | 0.78 | KMT2A (0.40) | CRHR1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL1563307 | 0.77 | GFER (0.50) | CRHR1SMN1; SMN2POLBLMNANQO2 | |
| SCHEMBL24915777 | 0.76 | MAPT (0.42) | CRHR1KMT2APOLBLMNANQO2 | |
| SCHEMBL5262975 | 0.73 | PDGFRB (0.42) | KMT2ANQO2MEN1CYP1A2CYP3A4 | |
| SCHEMBL29923449 | 0.73 | CYP3A4 (0.41) | CRHR1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL29923869 | 0.73 | PDGFRB (0.42) | KMT2ANQO2MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |